ビスフェノールA関連論文
[医療・医学など]
ビスフェノールAは食器や箸や缶コーヒーの容器にも使われている身近な化学物質ですが、環境ホルモンとして作用すると考えられています。最近母体から胎児あるいは乳児への移行が注目され、成長してからの影響も危惧されています。
私たちの研究グループの以下の業績も世界の主要な関係論文にも引用されており、研究成果が今後の研究にも役立つかと期待されます。未発表の研究成果もあるので、これから時間をかけてまとめていこうと思います。
1: Elevated serum bisphenol A levels under hyperandrogenic conditions may be caused by decreased UDP-glucuronosyltransferase activity. Takeuchi T, Tsutsumi O, Ikezuki Y, Kamei Y, Osuga Y, Fujiwara T, Takai Y, Momoeda M, Yano T, Taketani Y. Endocr J. 2006 Aug;53(4):485-91. Epub 2006 Jul 10.
2: Assessment of human contamination of estrogenic endocrine-disrupting chemicals and their risk for human reproduction. Tsutsumi O. J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):325-30. Epub 2005 Jan 26.
3: Differences in serum bisphenol a concentrations in premenopausal normal women and women with endometrial hyperplasia. Hiroi H, Tsutsumi O, Takeuchi T, Momoeda M, Ikezuki Y, Okamura A, Yokota H, Taketani Y. Endocr J. 2004 Dec;51(6):595-600.
4: Gender difference in serum bisphenol A levels may be caused by liver UDP-glucuronosyltransferase activity in rats. Takeuchi T, Tsutsumi O, Nakamura N, Ikezuki Y, Takai Y, Yano T, Taketani Y. Biochem Biophys Res Commun. 2004 Dec 10;325(2):549-54.
5: Positive relationship between androgen and the endocrine disruptor, bisphenol A, in normal women and women with ovarian dysfunction. Takeuchi T, Tsutsumi O, Ikezuki Y, Takai Y, Taketani Y. Endocr J. 2004 Apr;51(2):165-9.
6: Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure. Ikezuki Y, Tsutsumi O, Takai Y, Kamei Y, Taketani Y. Hum Reprod. 2002 Nov;17(11):2839-41.
7: The activity of bisphenol A depends on both the estrogen receptor subtype and the cell type. Kurosawa T, Hiroi H, Tsutsumi O, Ishikawa T, Osuga Y, Fujiwara T, Inoue S, Muramatsu M, Momoeda M, Taketani Y.
Endocr J. 2002 Aug;49(4):465-71.
8: Bisphenol A induces apoptosis and G2-to-M arrest of ovarian granulosa cells. Xu J, Osuga Y, Yano T, Morita Y, Tang X, Fujiwara T, Takai Y, Matsumi H, Koga K, Taketani Y, Tsutsumi O. Biochem Biophys Res Commun. 2002 Mar 29;292(2):456-62.
9: Serum bisphenol a concentrations showed gender differences, possibly linked to androgen levels. Takeuchi T, Tsutsumi O. Biochem Biophys Res Commun. 2002 Feb 15;291(1):76-8.
10: [Effects of endocrine disruptors on preimplantation embryo development] Tsutsumi O. Nippon Rinsho. 2000 Dec;58(12):2464-8. Review. Japanese.
11: Preimplantation exposure to bisphenol A advances postnatal development. Takai Y, Tsutsumi O, Ikezuki Y, Kamei Y, Osuga Y, Yano T, Taketan Y. Reprod Toxicol. 2001 Jan-Feb;15(1):71-4.
12: Estrogen receptor-mediated effects of a xenoestrogen, bisphenol A, on preimplantation mouse embryos. Takai Y, Tsutsumi O, Ikezuki Y, Hiroi H, Osuga Y, Momoeda M, Yano T, Taketani Y. Biochem Biophys Res Commun. 2000 Apr 21;270(3):918-21.
13: Differential interactions of bisphenol A and 17beta-estradiol with estrogen receptor alpha (ERalpha) and ERbeta.
Hiroi H, Tsutsumi O, Momoeda M, Takai Y, Osuga Y, Taketani Y.
Endocr J. 1999 Dec;46(6):773-8.
私たちの研究グループの以下の業績も世界の主要な関係論文にも引用されており、研究成果が今後の研究にも役立つかと期待されます。未発表の研究成果もあるので、これから時間をかけてまとめていこうと思います。
1: Elevated serum bisphenol A levels under hyperandrogenic conditions may be caused by decreased UDP-glucuronosyltransferase activity. Takeuchi T, Tsutsumi O, Ikezuki Y, Kamei Y, Osuga Y, Fujiwara T, Takai Y, Momoeda M, Yano T, Taketani Y. Endocr J. 2006 Aug;53(4):485-91. Epub 2006 Jul 10.
2: Assessment of human contamination of estrogenic endocrine-disrupting chemicals and their risk for human reproduction. Tsutsumi O. J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):325-30. Epub 2005 Jan 26.
3: Differences in serum bisphenol a concentrations in premenopausal normal women and women with endometrial hyperplasia. Hiroi H, Tsutsumi O, Takeuchi T, Momoeda M, Ikezuki Y, Okamura A, Yokota H, Taketani Y. Endocr J. 2004 Dec;51(6):595-600.
4: Gender difference in serum bisphenol A levels may be caused by liver UDP-glucuronosyltransferase activity in rats. Takeuchi T, Tsutsumi O, Nakamura N, Ikezuki Y, Takai Y, Yano T, Taketani Y. Biochem Biophys Res Commun. 2004 Dec 10;325(2):549-54.
5: Positive relationship between androgen and the endocrine disruptor, bisphenol A, in normal women and women with ovarian dysfunction. Takeuchi T, Tsutsumi O, Ikezuki Y, Takai Y, Taketani Y. Endocr J. 2004 Apr;51(2):165-9.
6: Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure. Ikezuki Y, Tsutsumi O, Takai Y, Kamei Y, Taketani Y. Hum Reprod. 2002 Nov;17(11):2839-41.
7: The activity of bisphenol A depends on both the estrogen receptor subtype and the cell type. Kurosawa T, Hiroi H, Tsutsumi O, Ishikawa T, Osuga Y, Fujiwara T, Inoue S, Muramatsu M, Momoeda M, Taketani Y.
Endocr J. 2002 Aug;49(4):465-71.
8: Bisphenol A induces apoptosis and G2-to-M arrest of ovarian granulosa cells. Xu J, Osuga Y, Yano T, Morita Y, Tang X, Fujiwara T, Takai Y, Matsumi H, Koga K, Taketani Y, Tsutsumi O. Biochem Biophys Res Commun. 2002 Mar 29;292(2):456-62.
9: Serum bisphenol a concentrations showed gender differences, possibly linked to androgen levels. Takeuchi T, Tsutsumi O. Biochem Biophys Res Commun. 2002 Feb 15;291(1):76-8.
10: [Effects of endocrine disruptors on preimplantation embryo development] Tsutsumi O. Nippon Rinsho. 2000 Dec;58(12):2464-8. Review. Japanese.
11: Preimplantation exposure to bisphenol A advances postnatal development. Takai Y, Tsutsumi O, Ikezuki Y, Kamei Y, Osuga Y, Yano T, Taketan Y. Reprod Toxicol. 2001 Jan-Feb;15(1):71-4.
12: Estrogen receptor-mediated effects of a xenoestrogen, bisphenol A, on preimplantation mouse embryos. Takai Y, Tsutsumi O, Ikezuki Y, Hiroi H, Osuga Y, Momoeda M, Yano T, Taketani Y. Biochem Biophys Res Commun. 2000 Apr 21;270(3):918-21.
13: Differential interactions of bisphenol A and 17beta-estradiol with estrogen receptor alpha (ERalpha) and ERbeta.
Hiroi H, Tsutsumi O, Momoeda M, Takai Y, Osuga Y, Taketani Y.
Endocr J. 1999 Dec;46(6):773-8.
2009年03月13日 23:55 [医療・医学など]
